A phosphate-targeted dinuclear Cu(II) complex combining major groove binding and oxidative DNA cleavage

Free radical generation is an inevitable consequence of aerobic existence and is implicated in a wide variety of pathological conditions including cancer, cardiovascular disease, ageing and neurodegenerative disorder. Free radicals can, however, be used to our advantage since their production is cat...

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Detalles Bibliográficos
Autores principales: Molphy, Zara, Montagner, Diego, Bhat, Satish S, Slator, Creina, Long, Conor, Erxleben, Andrea, Kellett, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212767/
https://www.ncbi.nlm.nih.gov/pubmed/30239938
http://dx.doi.org/10.1093/nar/gky806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212767/
https://www.ncbi.nlm.nih.gov/pubmed/30239938
http://dx.doi.org/10.1093/nar/gky806

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