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Codon-specific effects of tRNA anticodon loop modifications on translational misreading errors in the yeast Saccharomyces cerevisiae

Protein synthesis requires both high speed and accuracy to ensure a healthy cellular environment. Estimates of errors during protein synthesis in Saccharomyces cerevisiae have varied from 10(−3) to 10(−4) errors per codon. Here, we show that errors made by [Formula: see text] in yeast can vary 100-f...

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Detalles Bibliográficos
Autores principales: Joshi, Kartikeya, Bhatt, Monika J, Farabaugh, Philip J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212777/
https://www.ncbi.nlm.nih.gov/pubmed/30060218
http://dx.doi.org/10.1093/nar/gky664