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Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels

CONTEXT: Epigenetics may contribute to sex-specific differences in human liver metabolism. OBJECTIVE: To study the impact of sex on DNA methylation and gene expression in human liver. DESIGN/SETTING: Cross-sectional, Kuopio Obesity Surgery Study. PARTICIPANTS/INTERVENTION: We analyzed DNA methylatio...

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Detalles Bibliográficos
Autores principales: García-Calzón, Sonia, Perfilyev, Alexander, de Mello, Vanessa D, Pihlajamäki, Jussi, Ling, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212806/
https://www.ncbi.nlm.nih.gov/pubmed/29846646
http://dx.doi.org/10.1210/jc.2018-00423