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Chlorogenic Acid Targeting of the AKT PH Domain Activates AKT/GSK3β/FOXO1 Signaling and Improves Glucose Metabolism

Chlorogenic acid (CGA), a bioactive component in the human diet, is reported to exert beneficial effects on the regulation of glucose metabolism. This study was designed to investigate the specific target of CGA, and explore its underlying mechanisms. Beneficial effects of CGA in glucose metabolism...

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Detalles Bibliográficos
Autores principales: Gao, Jie, He, Xin, Ma, Yuejiao, Zhao, Xuezhi, Hou, Xiaotao, Hao, Erwei, Deng, Jiagang, Bai, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212807/
https://www.ncbi.nlm.nih.gov/pubmed/30249058
http://dx.doi.org/10.3390/nu10101366