A Secreted Bacterial Peptidylarginine Deiminase Can Neutralize Human Innate Immune Defenses

The keystone oral pathogen Porphyromonas gingivalis is associated with severe periodontitis. Intriguingly, this bacterium is known to secrete large amounts of an enzyme that converts peptidylarginine into citrulline residues. The present study was aimed at identifying possible functions of this citr...

Descripción completa

Detalles Bibliográficos
Autores principales: Stobernack, Tim, du Teil Espina, Marines, Mulder, Lianne M., Palma Medina, Laura M., Piebenga, Dillon R., Gabarrini, Giorgio, Zhao, Xin, Janssen, Koen M. J., Hulzebos, Jarnick, Brouwer, Elisabeth, Sura, Thomas, Becher, Dörte, van Winkelhoff, Arie Jan, Götz, Friedrich, Otto, Andreas, Westra, Johanna, van Dijl, Jan Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212822/
https://www.ncbi.nlm.nih.gov/pubmed/30377277
http://dx.doi.org/10.1128/mBio.01704-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212822/
https://www.ncbi.nlm.nih.gov/pubmed/30377277
http://dx.doi.org/10.1128/mBio.01704-18

Ejemplares similares