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Rapid high-resolution measurement of DNA replication timing by droplet digital PCR

Genomes are replicated in a reproducible temporal pattern. Current methods for assaying allele replication timing are time consuming and/or expensive. These include high-throughput sequencing which can be used to measure DNA copy number as a proxy for allele replication timing. Here, we use droplet...

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Detalles Bibliográficos
Autores principales: Batrakou, Dzmitry G, Heron, Emma D, Nieduszynski, Conrad A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212846/
https://www.ncbi.nlm.nih.gov/pubmed/29986073
http://dx.doi.org/10.1093/nar/gky590