Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension

Increased growth and proliferation of distal pulmonary artery vascular smooth muscle cells (PAVSMC) is an important pathological component of pulmonary arterial hypertension (PAH). Transforming Growth Factor-β (TGF-β) superfamily plays a critical role in PAH, but relative impacts of self-secreted Ac...

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Detalles Bibliográficos
Autores principales: Kudryashova, Tatiana V., Shen, Yuanjun, Pena, Andressa, Cronin, Emily, Okorie, Evelyn, Goncharov, Dmitry A., Goncharova, Elena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212879/
https://www.ncbi.nlm.nih.gov/pubmed/30274147
http://dx.doi.org/10.3390/ijms19102957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212879/
https://www.ncbi.nlm.nih.gov/pubmed/30274147
http://dx.doi.org/10.3390/ijms19102957

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