Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats

In this study, we investigated the effects of minocycline, a putative suppressor of microglial activation, on systemic lipopolysaccharide (LPS)-induced spinal cord inflammation, allodynia, and hyperalgesia in neonatal rats. Intraperitoneal (i.p.) injection of LPS (2 mg/kg) or sterile saline was perf...

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Detalles Bibliográficos
Autores principales: Hsieh, Cheng-Ta, Lee, Yih-Jing, Dai, Xiaoli, Ojeda, Norma Beatriz, Lee, Hyun Joon, Tien, Lu-Tai, Fan, Lir-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212885/
https://www.ncbi.nlm.nih.gov/pubmed/30262747
http://dx.doi.org/10.3390/ijms19102947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212885/
https://www.ncbi.nlm.nih.gov/pubmed/30262747
http://dx.doi.org/10.3390/ijms19102947

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