Cargando…

Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats

In this study, we investigated the effects of minocycline, a putative suppressor of microglial activation, on systemic lipopolysaccharide (LPS)-induced spinal cord inflammation, allodynia, and hyperalgesia in neonatal rats. Intraperitoneal (i.p.) injection of LPS (2 mg/kg) or sterile saline was perf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsieh, Cheng-Ta, Lee, Yih-Jing, Dai, Xiaoli, Ojeda, Norma Beatriz, Lee, Hyun Joon, Tien, Lu-Tai, Fan, Lir-Wan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212885/ https://www.ncbi.nlm.nih.gov/pubmed/30262747 http://dx.doi.org/10.3390/ijms19102947

Ejemplares similares

Pioglitazone Ameliorates Lipopolysaccharide-Induced Behavioral Impairment, Brain Inflammation, White Matter Injury and Mitochondrial Dysfunction in Neonatal Rats
por: Yeh, Jiann-Horng, et al.
Publicado: (2021)

Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide
por: Kaizaki, Asuka, et al.
Publicado: (2013)

Interleukin-1 Receptor Antagonist Reduces Neonatal Lipopolysaccharide-Induced Long-Lasting Neurobehavioral Deficits and Dopaminergic Neuronal Injury in Adult Rats
por: Pang, Yi, et al.
Publicado: (2015)

Oxidative Stress and Neurodevelopmental Outcomes in Rat Offspring with Intrauterine Growth Restriction Induced by Reduced Uterine Perfusion
por: Rains, Marcelo E., et al.
Publicado: (2021)

Minocycline and Risperidone Prevent Microglia Activation and Rescue Behavioral Deficits Induced by Neonatal Intrahippocampal Injection of Lipopolysaccharide in Rats
por: Zhu, Furong, et al.
Publicado: (2014)

Minocycline and sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation
por: Yang, Li-ping, et al.
Publicado: (2007)

Minocycline-Suppression of Early Peripheral Inflammation Reduces Hypoxia-Induced Neonatal Brain Injury
por: Min, Yingjun, et al.
Publicado: (2017)

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
por: Henry, Christopher J, et al.
Publicado: (2008)

Dexmedetomidine Alleviates Microglia-Induced Spinal Inflammation and Hyperalgesia in Neonatal Rats by Systemic Lipopolysaccharide Exposure
por: Wen, Wen, et al.
Publicado: (2021)

Intracerebral lipopolysaccharide induces neuroinflammatory change and augmented brain injury in growth-restricted neonatal rats
por: Campbell, Leigh R., et al.
Publicado: (2012)

Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids
por: Boisvert, Erin M., et al.
Publicado: (2019)

Minocycline attenuation of rat corpus callosum abnormality mediated by low-dose lipopolysaccharide-induced microglia activation
por: Zhang, Jingdong, et al.
Publicado: (2021)

Metformin reverse minocycline to inhibit minocycline-resistant Acinetobacter baumannii by destroy the outer membrane and enhance membrane potential in vitro
por: Guo, Tingting, et al.
Publicado: (2022)

Early Postnatal Lipopolysaccharide Exposure Leads to Enhanced Neurogenesis and Impaired Communicative Functions in Rats
por: Pang, Yi, et al.
Publicado: (2016)

Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury
por: Shultz, Robert B., et al.
Publicado: (2017)

Safety evaluation and pharmacodynamics of minocycline hydrochloride eye drops
por: Li, Xiaoli, et al.
Publicado: (2022)

Minocycline-induced hyperpigmentation
por: Fiscus, Valena, et al.
Publicado: (2014)

Neuroprotective Effects of Combined Treatment with Minocycline and Olfactory Ensheathing Cells Transplantation against Inflammation and Oxidative Stress after Spinal Cord Injury
por: Pourkhodadad, Soheila, et al.
Publicado: (2019)

Pretreatment with minocycline improves neurogenesis and behavior performance after midazolam exposure in neonatal rats
por: Giri, Praveen K., et al.
Publicado: (2018)

Neuroprotective effect of minocycline on rat retinal ischemia-reperfusion injury
por: Li, Xiaoli, et al.
Publicado: (2021)

Higher Lipopolysaccharide Binding Protein and Chemerin Concentrations Were Associated with Metabolic Syndrome Features in Pediatric Subjects with Abdominal Obesity during a Lifestyle Intervention
por: Marti, Amelia, et al.
Publicado: (2021)

Minocycline Down-Regulates Topical Mucosal Inflammation during the Application of Microbicide Candidates
por: Li, Liangzhu, et al.
Publicado: (2012)

Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury
por: Abcouwer, Steven F, et al.
Publicado: (2013)

The anti-inflammatory effect of minocycline on endotoxin-induced uveitis and retinal inflammation in rats
por: Yuan, Zhaohui, et al.
Publicado: (2019)

Erythropoietin Ameliorates Neonatal Hypoxia-Ischemia-Induced Neurobehavioral Deficits, Neuroinflammation, and Hippocampal Injury in the Juvenile Rat
por: Lan, Kuo-Mao, et al.
Publicado: (2016)

Prevention of hypoglycemia-induced neuronal death by minocycline
por: Won, Seok Joon, et al.
Publicado: (2012)

Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures
por: Piotrowska, Anna, et al.
Publicado: (2017)

Use of minocycline in viral infections
por: Dutta, Kallol, et al.
Publicado: (2011)

Minocycline-induced scleral pigmentation
por: Al Hussein Al Awamlh, Sara, et al.
Publicado: (2022)

Minocycline-Induced Ocular Ochronosis
por: Baaklini, Carla, et al.
Publicado: (2023)

Minocycline-Induced Hyperpigmentation of Nails
por: Varghese, Kevin, et al.
Publicado: (2023)

Protective Effect of Minocycline Against Cisplatin-induced Ototoxicity
por: Lee, Chi-Kyou, et al.
Publicado: (2011)

Minocycline promotes the generation of dendritic cells with regulatory properties
por: Kim, Narae, et al.
Publicado: (2016)

Hispidulin Inhibits the Vascular Inflammation Triggered by Porphyromonas gingivalis Lipopolysaccharide
por: Kim, Yeon, et al.
Publicado: (2023)

Neuroprotection by Abdominal Ultrasound in Lipopolysaccharide-Induced Systemic Inflammation
por: Song, Wen-Shin, et al.
Publicado: (2023)

Tolerogenic dendritic cells are efficiently generated using minocycline and dexamethasone
por: Lee, Jae-Hee, et al.
Publicado: (2017)

Tetracycline Derivative Minocycline Inhibits Autophagy and Inflammation in Concanavalin-A-Activated Human Hepatoma Cells
por: Desjarlais, Michel, et al.
Publicado: (2014)

Improved outcome of EAN, an animal model of GBS, through amelioration of peripheral and central inflammation by minocycline
por: Zhang, Zhi-Yuan, et al.
Publicado: (2009)

Delayed Minocycline Treatment Ameliorates Hydrocephalus Development and Choroid Plexus Inflammation in Spontaneously Hypertensive Rats
por: Hao, Xiaodi, et al.
Publicado: (2022)

Berberin sustained-release nanoparticles were enriched in infarcted rat myocardium and resolved inflammation
por: Zhu, Ke, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_olt3mcsbdeg6rtgtp16fuh64oq