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Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells

Thioredoxin (Trx) overexpression is known to be a cause of chemotherapy resistance in various tumor entities. However, Trx effects on resistance are complex and depend strictly on tissue type. In the present study, we analyzed the impact of the Trx system on intrinsic chemoresistance of human gliobl...

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Detalles Bibliográficos
Autores principales: Haas, Bodo, Schütte, Lena, Wos-Maganga, Maria, Weickhardt, Sandra, Timmer, Marco, Eckstein, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212897/
https://www.ncbi.nlm.nih.gov/pubmed/30248944
http://dx.doi.org/10.3390/ijms19102874