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MicroRNA-204 Is Necessary for Aldosterone-Stimulated T-Type Calcium Channel Expression in Cardiomyocytes

Activation of the mineralocorticoid receptor (MR) in the heart is considered to be a cardiovascular risk factor. MR activation leads to heart hypertrophy and arrhythmia. In ventricular cardiomyocytes, aldosterone induces a profound remodeling of ion channel expression, in particular, an increase in...

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Detalles Bibliográficos
Autores principales: Koyama, Riko, Mannic, Tiphaine, Ito, Jumpei, Amar, Laurence, Zennaro, Maria-Christina, Rossier, Michel Florian, Maturana, Andrés Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212903/
https://www.ncbi.nlm.nih.gov/pubmed/30262720
http://dx.doi.org/10.3390/ijms19102941