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MicroRNA-204 Is Necessary for Aldosterone-Stimulated T-Type Calcium Channel Expression in Cardiomyocytes
Activation of the mineralocorticoid receptor (MR) in the heart is considered to be a cardiovascular risk factor. MR activation leads to heart hypertrophy and arrhythmia. In ventricular cardiomyocytes, aldosterone induces a profound remodeling of ion channel expression, in particular, an increase in...
Autores principales: | Koyama, Riko, Mannic, Tiphaine, Ito, Jumpei, Amar, Laurence, Zennaro, Maria-Christina, Rossier, Michel Florian, Maturana, Andrés Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212903/ https://www.ncbi.nlm.nih.gov/pubmed/30262720 http://dx.doi.org/10.3390/ijms19102941 |
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