Synthesis and Biological Evaluation of Thalidomide Derivatives as Potential Anti-Psoriasis Agents

Several thalidomide derivatives were synthesized and evaluated for their anti-inflammatory activity. Introduction of the benzyl group to the parent thalidomide is unfavorable in which 2-(1-benzyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (4a) was inactivated. However, the inhibitory activities o...

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Detalles Bibliográficos
Autores principales: Tang, Kai-Wei, Lin, Zih-Chan, Chen, Yeh-Long, Tzeng, Cherng-Chyi, Fang, Jia-You, Tseng, Chih-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212999/
https://www.ncbi.nlm.nih.gov/pubmed/30301277
http://dx.doi.org/10.3390/ijms19103061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212999/
https://www.ncbi.nlm.nih.gov/pubmed/30301277
http://dx.doi.org/10.3390/ijms19103061

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