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Bioelectrical Impedance Analysis Results for Estimating Body Composition Are Associated with Glucose Metabolism Following Laparoscopic Sleeve Gastrectomy in Obese Japanese Patients

We investigated the association between body composition and changes in glucose metabolism following laparoscopic sleeve gastrectomy (LSG) in obese Japanese patients. Thirty-two Class III obese patients were assessed before LSG and 3, 6, and 12 months postoperatively. Variables including fat mass (F...

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Autores principales: Ozeki, Yoshinori, Masaki, Takayuki, Yoshida, Yuichi, Okamoto, Mitsuhiro, Anai, Manabu, Gotoh, Koro, Endo, Yuichi, Ohta, Masayuki, Inomata, Masafumi, Shibata, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213007/
https://www.ncbi.nlm.nih.gov/pubmed/30297607
http://dx.doi.org/10.3390/nu10101456
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author Ozeki, Yoshinori
Masaki, Takayuki
Yoshida, Yuichi
Okamoto, Mitsuhiro
Anai, Manabu
Gotoh, Koro
Endo, Yuichi
Ohta, Masayuki
Inomata, Masafumi
Shibata, Hirotaka
author_facet Ozeki, Yoshinori
Masaki, Takayuki
Yoshida, Yuichi
Okamoto, Mitsuhiro
Anai, Manabu
Gotoh, Koro
Endo, Yuichi
Ohta, Masayuki
Inomata, Masafumi
Shibata, Hirotaka
author_sort Ozeki, Yoshinori
collection PubMed
description We investigated the association between body composition and changes in glucose metabolism following laparoscopic sleeve gastrectomy (LSG) in obese Japanese patients. Thirty-two Class III obese patients were assessed before LSG and 3, 6, and 12 months postoperatively. Variables including fat mass (FM), % body fat (%FM), total and skeletal muscle mass (MM), the ratio of lower extremity MM to body weight (BW) (L/W), and the ratio of upper extremity MM to BW (U/W) were measured while using bioelectrical impedance analysis (BIA). LSG significantly decreased BW, FM, and %FM in all time periods observed after surgery with concomitant improvements in metabolic markers. MM was decreased at three months but maintained from 3–12 months post-surgery. Importantly, %MM, U/W, and the L/W ratio increased after LSG. Furthermore, change in FM was positively correlated with change in BW 12 months after LSG, whereas changes in %MM were negatively correlated with fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c). Finally, multivariable stepwise regression analyses showed that changes in % total MM was an independent determinant of FPG and change in % skeletal MM was a significant independent determinant of HbA1c in Class III obese Japanese patients after LSG.
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spelling pubmed-62130072018-11-06 Bioelectrical Impedance Analysis Results for Estimating Body Composition Are Associated with Glucose Metabolism Following Laparoscopic Sleeve Gastrectomy in Obese Japanese Patients Ozeki, Yoshinori Masaki, Takayuki Yoshida, Yuichi Okamoto, Mitsuhiro Anai, Manabu Gotoh, Koro Endo, Yuichi Ohta, Masayuki Inomata, Masafumi Shibata, Hirotaka Nutrients Article We investigated the association between body composition and changes in glucose metabolism following laparoscopic sleeve gastrectomy (LSG) in obese Japanese patients. Thirty-two Class III obese patients were assessed before LSG and 3, 6, and 12 months postoperatively. Variables including fat mass (FM), % body fat (%FM), total and skeletal muscle mass (MM), the ratio of lower extremity MM to body weight (BW) (L/W), and the ratio of upper extremity MM to BW (U/W) were measured while using bioelectrical impedance analysis (BIA). LSG significantly decreased BW, FM, and %FM in all time periods observed after surgery with concomitant improvements in metabolic markers. MM was decreased at three months but maintained from 3–12 months post-surgery. Importantly, %MM, U/W, and the L/W ratio increased after LSG. Furthermore, change in FM was positively correlated with change in BW 12 months after LSG, whereas changes in %MM were negatively correlated with fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c). Finally, multivariable stepwise regression analyses showed that changes in % total MM was an independent determinant of FPG and change in % skeletal MM was a significant independent determinant of HbA1c in Class III obese Japanese patients after LSG. MDPI 2018-10-08 /pmc/articles/PMC6213007/ /pubmed/30297607 http://dx.doi.org/10.3390/nu10101456 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ozeki, Yoshinori
Masaki, Takayuki
Yoshida, Yuichi
Okamoto, Mitsuhiro
Anai, Manabu
Gotoh, Koro
Endo, Yuichi
Ohta, Masayuki
Inomata, Masafumi
Shibata, Hirotaka
Bioelectrical Impedance Analysis Results for Estimating Body Composition Are Associated with Glucose Metabolism Following Laparoscopic Sleeve Gastrectomy in Obese Japanese Patients
title Bioelectrical Impedance Analysis Results for Estimating Body Composition Are Associated with Glucose Metabolism Following Laparoscopic Sleeve Gastrectomy in Obese Japanese Patients
title_full Bioelectrical Impedance Analysis Results for Estimating Body Composition Are Associated with Glucose Metabolism Following Laparoscopic Sleeve Gastrectomy in Obese Japanese Patients
title_fullStr Bioelectrical Impedance Analysis Results for Estimating Body Composition Are Associated with Glucose Metabolism Following Laparoscopic Sleeve Gastrectomy in Obese Japanese Patients
title_full_unstemmed Bioelectrical Impedance Analysis Results for Estimating Body Composition Are Associated with Glucose Metabolism Following Laparoscopic Sleeve Gastrectomy in Obese Japanese Patients
title_short Bioelectrical Impedance Analysis Results for Estimating Body Composition Are Associated with Glucose Metabolism Following Laparoscopic Sleeve Gastrectomy in Obese Japanese Patients
title_sort bioelectrical impedance analysis results for estimating body composition are associated with glucose metabolism following laparoscopic sleeve gastrectomy in obese japanese patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213007/
https://www.ncbi.nlm.nih.gov/pubmed/30297607
http://dx.doi.org/10.3390/nu10101456
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