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Non-Canonical Regulation of Type I Collagen through Promoter Binding of SOX2 and Its Contribution to Ameliorating Pulmonary Fibrosis by Butylidenephthalide

Pulmonary fibrosis is a fatal respiratory disease that gradually leads to dyspnea, mainly accompanied by excessive collagen production in the fibroblast and myofibroblast through mechanisms such as abnormal alveolar epithelial cells remodeling and stimulation of the extracellular matrix (ECM). Our r...

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Detalles Bibliográficos
Autores principales: Chuang, Hong-Meng, Ho, Li-Ing, Huang, Mao-Hsuan, Huang, Kun-Lun, Chiou, Tzyy-Wen, Lin, Shinn-Zong, Su, Hong-Lin, Harn, Horng-Jyh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213013/
https://www.ncbi.nlm.nih.gov/pubmed/30287739
http://dx.doi.org/10.3390/ijms19103024