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A Thermodynamic Model for Multivalency in 14-3-3 Protein–Protein Interactions

[Image: see text] Protein–protein interactions (PPIs) are at the core of molecular control over cellular function. Multivalency in PPI formation, such as via proteins with multiple binding sites and different valencies, requires fundamental understanding to address correlated challenges in pathologi...

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Detalles Bibliográficos
Autores principales: Stevers, Loes M., de Vink, Pim J., Ottmann, Christian, Huskens, Jurriaan, Brunsveld, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213025/
https://www.ncbi.nlm.nih.gov/pubmed/30296824
http://dx.doi.org/10.1021/jacs.8b09618