Insights into the Structural Requirements of 2(S)-Amino-6-Boronohexanoic Acid Derivatives as Arginase I Inhibitors: 3D-QSAR, Docking, and Interaction Fingerprint Studies

Human arginase I (hARGI) is an important enzyme involved in the urea cycle; its overexpression has been associated to cardiovascular and cerebrovascular diseases. In the last years, several congeneric sets of hARGI inhibitors have been reported with possible beneficial roles for the cardiovascular s...

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Detalles Bibliográficos
Autores principales: Velázquez-Libera, José Luis, Navarro-Retamal, Carlos, Caballero, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213053/
https://www.ncbi.nlm.nih.gov/pubmed/30274146
http://dx.doi.org/10.3390/ijms19102956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213053/
https://www.ncbi.nlm.nih.gov/pubmed/30274146
http://dx.doi.org/10.3390/ijms19102956

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