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Attempt to Untangle the Prion-Like Misfolding Mechanism for Neurodegenerative Diseases
The misfolding and aggregation of proteins is the neuropathological hallmark for numerous diseases including Alzheimer’s disease, Parkinson’s disease, and prion diseases. It is believed that misfolded and abnormal β-sheets forms of wild-type proteins are the vectors of these diseases by acting as se...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213118/ https://www.ncbi.nlm.nih.gov/pubmed/30304819 http://dx.doi.org/10.3390/ijms19103081 |