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Pharmacological Inhibition of Class IIA HDACs by LMK-235 in Pancreatic Neuroendocrine Tumor Cells

Histone deacetylases (HDACs) play a key role in epigenetic mechanisms in health and disease and their dysfunction is implied in several cancer entities. Analysis of expression patterns in pancreatic neuroendocrine tumors (pNETs) indicated HDAC5 to be a potential target for future therapies. As a fir...

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Detalles Bibliográficos
Autores principales: Wanek, Julia, Gaisberger, Martin, Beyreis, Marlena, Mayr, Christian, Helm, Katharina, Primavesi, Florian, Jäger, Tarkan, Di Fazio, Pietro, Jakab, Martin, Wagner, Andrej, Neureiter, Daniel, Kiesslich, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213165/
https://www.ncbi.nlm.nih.gov/pubmed/30321986
http://dx.doi.org/10.3390/ijms19103128