New Mammalian Target of Rapamycin (mTOR) Modulators Derived from Natural Product Databases and Marine Extracts by Using Molecular Docking Techniques

Mammalian target of rapamycin (mTOR) is a PI3K-related serine/threonine protein kinase that functions as a master regulator of cellular growth and metabolism, in response to nutrient and hormonal stimuli. mTOR functions in two distinct complexes—mTORC1 is sensitive to rapamycin, while, mTORC2 is ins...

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Detalles Bibliográficos
Autores principales: Ruiz-Torres, Verónica, Losada-Echeberría, Maria, Herranz-López, Maria, Barrajón-Catalán, Enrique, Galiano, Vicente, Micol, Vicente, Encinar, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213183/
https://www.ncbi.nlm.nih.gov/pubmed/30326670
http://dx.doi.org/10.3390/md16100385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213183/
https://www.ncbi.nlm.nih.gov/pubmed/30326670
http://dx.doi.org/10.3390/md16100385

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