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New Mammalian Target of Rapamycin (mTOR) Modulators Derived from Natural Product Databases and Marine Extracts by Using Molecular Docking Techniques

Mammalian target of rapamycin (mTOR) is a PI3K-related serine/threonine protein kinase that functions as a master regulator of cellular growth and metabolism, in response to nutrient and hormonal stimuli. mTOR functions in two distinct complexes—mTORC1 is sensitive to rapamycin, while, mTORC2 is ins...

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Detalles Bibliográficos
Autores principales:	Ruiz-Torres, Verónica, Losada-Echeberría, Maria, Herranz-López, Maria, Barrajón-Catalán, Enrique, Galiano, Vicente, Micol, Vicente, Encinar, José Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213183/ https://www.ncbi.nlm.nih.gov/pubmed/30326670 http://dx.doi.org/10.3390/md16100385

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