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Apoptosis Induction by dsRNA-Dependent Protein Kinase R (PKR) in EPC Cells via Caspase 8 and 9 Pathways

dsRNA-dependent protein kinase R (PKR) is an interferon-inducible protein that mediates antiviral effects and induces apoptosis. We studied PKR-related apoptosis mechanisms by transfecting wild type pcDNA-carp-wtPKR, a catalytically inactive mutant pcDNA-mut-carpPKR, and empty plasmid in Epithelioma...

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Detalles Bibliográficos
Autores principales: Xu, Cheng, Gamil, Amr A. A., Munang’andu, Hetron Mweemba, Evensen, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213184/
https://www.ncbi.nlm.nih.gov/pubmed/30261686
http://dx.doi.org/10.3390/v10100526