ABD-Derived Protein Blockers of Human IL-17 Receptor A as Non-IgG Alternatives for Modulation of IL-17-Dependent Pro-Inflammatory Axis

Interleukin 17 (IL-17) and its cognate receptor A (IL-17RA) play a crucial role in Th17 cells-mediated pro-inflammatory pathway and pathogenesis of several autoimmune disorders including psoriasis. IL-17 is mainly produced by activated Th-17 helper cells upon stimulation by IL-23 and, via binding to...

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Detalles Bibliográficos
Autores principales: Hlavničková, Marie, Kuchař, Milan, Osička, Radim, Vaňková, Lucie, Petroková, Hana, Malý, Michal, Černý, Jiří, Arenberger, Petr, Malý, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213189/
https://www.ncbi.nlm.nih.gov/pubmed/30304852
http://dx.doi.org/10.3390/ijms19103089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213189/
https://www.ncbi.nlm.nih.gov/pubmed/30304852
http://dx.doi.org/10.3390/ijms19103089

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