Efficacy Evaluation of Combination Treatment Using Gemcitabine and Radioimmunotherapy with (90)Y-Labeled Fully Human Anti-CD147 Monoclonal Antibody 059-053 in a BxPC-3 Xenograft Mouse Model of Refractory Pancreatic Cancer

The poor prognosis of pancreatic cancer requires the development of more effective therapy. CD147 expresses in pancreatic cancer with high incidence and has a crucial role in invasion and metastasis. We developed a fully human monoclonal antibody (059-053) with high affinity for CD147. Here we evalu...

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Detalles Bibliográficos
Autores principales: Sugyo, Aya, Tsuji, Atsushi B., Sudo, Hitomi, Koizumi, Mitsuru, Ukai, Yoshinori, Kurosawa, Gene, Kurosawa, Yoshikazu, Saga, Tsuneo, Higashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213240/
https://www.ncbi.nlm.nih.gov/pubmed/30274301
http://dx.doi.org/10.3390/ijms19102979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213240/
https://www.ncbi.nlm.nih.gov/pubmed/30274301
http://dx.doi.org/10.3390/ijms19102979

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