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Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway

Humanin (HN) is a novel 24-amino acid peptide that protects neurons against N-methyl-d-aspartate (NMDA)-induced toxicity. However, the contribution of the different mitogen-activated protein kinases (MAPKs) signals to HN neuroprotection against NMDA neurotoxicity remains unclear. The present study w...

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Detalles Bibliográficos
Autores principales: Yang, Xiaorong, Zhang, Hongmei, Wu, Jinzi, Yin, Litian, Yan, Liang-Jun, Zhang, Ce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213259/
https://www.ncbi.nlm.nih.gov/pubmed/30274308
http://dx.doi.org/10.3390/ijms19102982