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Pioglitazone Protects Mesenchymal Stem Cells against P-Cresol-Induced Mitochondrial Dysfunction via Up-Regulation of PINK-1

Mesenchymal stem cells (MSC) could be a candidate for cell-based therapy in chronic kidney disease (CKD); however, the uremic toxin in patients with CKD restricts the therapeutic efficacy of MSCs. To address this problem, we explored the effect of pioglitazone as a measure against exposure to the ur...

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Detalles Bibliográficos
Autores principales: Yoon, Yeo Min, Han, Yong-Seok, Yun, Chul Won, Lee, Jun Hee, Kim, Rang, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213327/
https://www.ncbi.nlm.nih.gov/pubmed/30250007
http://dx.doi.org/10.3390/ijms19102898