Cargando…

Pioglitazone Protects Mesenchymal Stem Cells against P-Cresol-Induced Mitochondrial Dysfunction via Up-Regulation of PINK-1

Mesenchymal stem cells (MSC) could be a candidate for cell-based therapy in chronic kidney disease (CKD); however, the uremic toxin in patients with CKD restricts the therapeutic efficacy of MSCs. To address this problem, we explored the effect of pioglitazone as a measure against exposure to the ur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoon, Yeo Min, Han, Yong-Seok, Yun, Chul Won, Lee, Jun Hee, Kim, Rang, Lee, Sang Hun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213327/ https://www.ncbi.nlm.nih.gov/pubmed/30250007 http://dx.doi.org/10.3390/ijms19102898

Ejemplares similares

Pioglitazone Improves the Function of Human Mesenchymal Stem Cells in Chronic Kidney Disease Patients
por: Yoon, Yeo Min, et al.
Publicado: (2019)

Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis
por: Lee, Jun Hee, et al.
Publicado: (2018)

Tauroursodeoxycholic Acid Protects against the Effects of P-Cresol-Induced Reactive Oxygen Species via the Expression of Cellular Prion Protein
por: Yun, Seung Pil, et al.
Publicado: (2018)

Knockdown of CK2α reduces P-cresol-induced fibrosis in human renal proximal tubule epithelial cells via the downregulation of profilin-1
por: Yoon, Yeo Min, et al.
Publicado: (2020)

Melatonin Rescues Mesenchymal Stem Cells from Senescence Induced by the Uremic Toxin p-Cresol via Inhibiting mTOR-Dependent Autophagy
por: Yun, Seung Pil, et al.
Publicado: (2018)

Melatonin suppresses senescence‐derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L–mitophagy pathway
por: Lee, Jun Hee, et al.
Publicado: (2020)

Melatonin Suppresses Renal Cortical Fibrosis by Inhibiting Cytoskeleton Reorganization and Mitochondrial Dysfunction through Regulation of miR-4516
por: Yoon, Yeo Min, et al.
Publicado: (2020)

Co-Administration of Melatonin Effectively Enhances the Therapeutic Effects of Pioglitazone on Mesenchymal Stem Cells Undergoing Indoxyl Sulfate-Induced Senescence through Modulation of Cellular Prion Protein Expression
por: Han, Yong Seok, et al.
Publicado: (2018)

Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis
por: Yoon, Yeo Min, et al.
Publicado: (2021)

Hypoxia-induced expression of cellular prion protein improves the therapeutic potential of mesenchymal stem cells
por: Han, Yong-Seok, et al.
Publicado: (2016)

Role of endothelial microvesicles released by p-cresol on endothelial dysfunction
por: Guerrero, Fatima, et al.
Publicado: (2020)

The Treatment of Cholera by Cresol
por: Palmer, F. J.
Publicado: (1924)

Analysis of Dispersion of Carbon Nanotubes in m-Cresol
por: Im, Jaegyun, et al.
Publicado: (2022)

Reproductive toxicology. o-Cresol.
Publicado: (1997)

The Treatment of Bacillary Dysentery by Cresol
por: Gupta, C. C. Das
Publicado: (1926)

The Treatment of Cholera by Acid and Cresol
por: Palmer, F. J.
Publicado: (1928)

The Treatment of Cholera by Cresol and Acid
por: Palmer, F. J.
Publicado: (1925)

TUDCA-Treated Mesenchymal Stem Cells Protect against ER Stress in the Hippocampus of a Murine Chronic Kidney Disease Model
por: Lee, Jun Hee, et al.
Publicado: (2019)

Exosomes isolated from melatonin-stimulated mesenchymal stem cells improve kidney function by regulating inflammation and fibrosis in a chronic kidney disease mouse model
por: Yea, Ji-Hye, et al.
Publicado: (2021)

Melatonin protects mesenchymal stem cells from autophagy‐mediated death under ischaemic ER‐stress conditions by increasing prion protein expression
por: Lee, Jun Hee, et al.
Publicado: (2018)

Electrochemical Study of Iodide in the Presence of Phenol and o-Cresol: Application to the Catalytic Determination of Phenol and o-Cresol
por: Fotouhi, Lida, et al.
Publicado: (2004)

Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells
por: Lee, Jun Hee, et al.
Publicado: (2016)

Reproductive toxicology. m-/p-cresol.
Publicado: (1997)

Gravid females of the mosquito Aedes aegypti avoid oviposition on m-cresol in the presence of the deterrent isomer p-cresol
por: Afify, Ali, et al.
Publicado: (2014)

TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency
por: Flinn, Laura J., et al.
Publicado: (2014)

Effects of p-Cresol on Oxidative Stress, Glutathione Depletion, and Necrosis in HepaRG Cells: Comparisons to Other Uremic Toxins and the Role of p-Cresol Glucuronide Formation
por: Zhu, Sang, et al.
Publicado: (2021)

P-cresol and Indoxyl Sulfate Impair Osteogenic Differentiation by Triggering Mesenchymal Stem Cell Senescence
por: Kamprom, Witchayapon, et al.
Publicado: (2021)

Hypoxic Preconditioning Promotes the Bioactivities of Mesenchymal Stem Cells via the HIF-1α-GRP78-Akt Axis
por: Lee, Jun Hee, et al.
Publicado: (2017)

Cripto Enhances Proliferation and Survival of Mesenchymal Stem Cells by Up-Regulating JAK2/STAT3 Pathway in a GRP78-Dependent Manner
por: Yun, SeungPil, et al.
Publicado: (2018)

A Note on the Disinfestation of Houses by Fumigation with Cresol
por: Lal, R. B., et al.
Publicado: (1925)

Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease
por: Costa, A C, et al.
Publicado: (2013)

PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control
por: Wu, You, et al.
Publicado: (2023)

The Risk of Bladder Cancer in Korean Diabetic Subjects Treated with Pioglitazone
por: Song, Sun Ok, et al.
Publicado: (2012)

PINK1-Parkin Pathway Activity Is Regulated by Degradation of PINK1 in the Mitochondrial Matrix
por: Thomas, Ruth E., et al.
Publicado: (2014)

PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control
por: Zhuang, Na, et al.
Publicado: (2016)

Pioglitazone Ameliorates Lipopolysaccharide-Induced Behavioral Impairment, Brain Inflammation, White Matter Injury and Mitochondrial Dysfunction in Neonatal Rats
por: Yeh, Jiann-Horng, et al.
Publicado: (2021)

PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis
por: Yang, Weili, et al.
Publicado: (2021)

Notch1 Protects against Ischemic-Reperfusion Injury by Suppressing PTEN-Pink1-Mediated Mitochondrial Dysfunction and Mitophagy
por: Xu, Qirong, et al.
Publicado: (2022)

Pioglitazone-Primed Mesenchymal Stem Cells Stimulate Cell Proliferation, Collagen Synthesis and Matrix Gene Expression in Tenocytes
por: Kim, Won, et al.
Publicado: (2019)

Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis
por: Patel, Avignat S., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qn3jiitfmlikscq4m928e7s654