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Prostaglandin D(2) Induces Ca(2+) Sensitization of Contraction without Affecting Cytosolic Ca(2+) Level in Bronchial Smooth Muscle

Prostaglandin D(2) (PGD(2)) is one of the key lipid mediators of allergic airway inflammation, including bronchial asthma. However, the role of PGD(2) in the pathogenesis of asthma is not fully understood. In the present study, the effect of PGD(2) on smooth muscle contractility of the airways was d...

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Detalles Bibliográficos
Autores principales: Suto, Wataru, Ando, Yusuke, Hirabayashi, Takahiro, Takenoya, Fumiko, Shioda, Seiji, Kamei, Junzo, Sakai, Hiroyasu, Chiba, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213397/
https://www.ncbi.nlm.nih.gov/pubmed/30301147
http://dx.doi.org/10.3390/ijms19103036