A Novel Naphthyridine Derivative, 3u, Induces Necroptosis at Low Concentrations and Apoptosis at High Concentrations in Human Melanoma A375 Cells

Naphthyridine derivatives are a widely-used class of heterocycles due to their pharmacological activities. A novel compound (10-Methoxy-1,2,3,4-tetrahydrobenzo(g)(1,3) diazepino(1,2-a)-(1,8)naphthyridin-6-yl)(phenyl) methanone (named 3u), showed good anticancer activity in the human malignant melano...

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Detalles Bibliográficos
Autores principales: Kong, Qinghong, Lv, Jianxin, Yan, Shengjiao, Chang, Kwen-Jen, Wang, Guanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213440/
https://www.ncbi.nlm.nih.gov/pubmed/30274263
http://dx.doi.org/10.3390/ijms19102975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213440/
https://www.ncbi.nlm.nih.gov/pubmed/30274263
http://dx.doi.org/10.3390/ijms19102975

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