Investigating Functional Roles for Positive Feedback and Cellular Heterogeneity in the Type I Interferon Response to Viral Infection

Secretion of type I interferons (IFN) by infected cells mediates protection against many viruses, but prolonged or excessive type I IFN secretion can lead to immune pathology. A proper type I IFN response must therefore maintain a balance between protection and excessive IFN secretion. It has been w...

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Detalles Bibliográficos
Autores principales: Leviyang, Sivan, Griva, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213501/
https://www.ncbi.nlm.nih.gov/pubmed/30241427
http://dx.doi.org/10.3390/v10100517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213501/
https://www.ncbi.nlm.nih.gov/pubmed/30241427
http://dx.doi.org/10.3390/v10100517

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