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Maternal Choline and Betaine Supplementation Modifies the Placental Response to Hyperglycemia in Mice and Human Trophoblasts

Gestational diabetes mellitus (GDM) is characterized by excessive placental fat and glucose transport, resulting in fetal overgrowth. Earlier we demonstrated that maternal choline supplementation normalizes fetal growth in GDM mice at mid-gestation. In this study, we further assess how choline and i...

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Detalles Bibliográficos
Autores principales: Nanobashvili, Khatia, Jack-Roberts, Chauntelle, Bretter, Rachel, Jones, Naudia, Axen, Kathleen, Saxena, Anjana, Blain, Kali, Jiang, Xinyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213524/
https://www.ncbi.nlm.nih.gov/pubmed/30326592
http://dx.doi.org/10.3390/nu10101507