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Filamentous Aggregates of Tau Proteins Fulfil Standard Amyloid Criteria Provided by the Fuzzy Oil Drop (FOD) Model

Abnormal filamentous aggregates that are formed by tangled tau protein turn out to be classic amyloid fibrils, meeting all the criteria defined under the fuzzy oil drop model in the context of amyloid characterization. The model recognizes amyloids as linear structures where local hydrophobicity min...

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Detalles Bibliográficos
Autores principales: Dułak, Dawid, Gadzała, Małgorzata, Banach, Mateusz, Ptak, Magdalena, Wiśniowski, Zdzisław, Konieczny, Leszek, Roterman, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213535/
https://www.ncbi.nlm.nih.gov/pubmed/30257460
http://dx.doi.org/10.3390/ijms19102910