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The Role of Stroma in Cholangiocarcinoma: The Intriguing Interplay between Fibroblastic Component, Immune Cell Subsets and Tumor Epithelium

Cholangiocarcinoma (CCA) is a severe and mostly intractable adenocarcinoma of biliary epithelial cells. A typical feature of CCA is its highly desmoplastic microenvironment containing fibrogenic connective tissue and an abundance of immune cells (T lymphocytes, Natural Killer (NK) cells, and macroph...

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Detalles Bibliográficos
Autores principales: Gentilini, Alessandra, Pastore, Mirella, Marra, Fabio, Raggi, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213545/
https://www.ncbi.nlm.nih.gov/pubmed/30249019
http://dx.doi.org/10.3390/ijms19102885