Immune Response Targeting Sjögren’s Syndrome Antigen Ro52 Suppresses Tear Production in Female Mice

Autoantibodies reactive against Ro52 are present in 70% of Sjögren’s syndrome patients and are associated with higher disease severity. However, their role in causing aqueous deficient dry eye, a major cause for morbidity in Sjögren’s syndrome, is unclear. To investigate whether immune responses tar...

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Detalles Bibliográficos
Autores principales: Trzeciak, Marta, Bagavant, Harini, Papinska, Joanna, Deshmukh, Umesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213551/
https://www.ncbi.nlm.nih.gov/pubmed/30261673
http://dx.doi.org/10.3390/ijms19102935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213551/
https://www.ncbi.nlm.nih.gov/pubmed/30261673
http://dx.doi.org/10.3390/ijms19102935

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