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Probing the Lipid Annular Belt by Gas‐Phase Dissociation of Membrane Proteins in Nanodiscs

Interactions between membrane proteins and lipids are often crucial for structure and function yet difficult to define because of their dynamic and heterogeneous nature. Here, we use mass spectrometry to demonstrate that membrane protein oligomers ejected from nanodiscs in the gas phase retain large...

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Detalles Bibliográficos
Autores principales: Marty, Michael T., Hoi, Kin Kuan, Gault, Joseph, Robinson, Carol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213558/
https://www.ncbi.nlm.nih.gov/pubmed/30416215
http://dx.doi.org/10.1002/ange.201508289