The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1β by Human Cytomegalovirus through Inhibition of NF-kB Activity

Interleukin-1β (IL-1β) is a key effector of the inflammasome complex in response to pathogens and danger signals. Although it is well known that assembly of the inflammasome triggers proteolytic cleavage of the biologically inactive precursor pro-IL-1β into its mature secreted form, the mechanism by...

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Detalles Bibliográficos
Autores principales: Biolatti, Matteo, Dell’Oste, Valentina, Scutera, Sara, Gugliesi, Francesca, Griffante, Gloria, De Andrea, Marco, Musso, Tiziana, Landolfo, Santo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213739/
https://www.ncbi.nlm.nih.gov/pubmed/30332797
http://dx.doi.org/10.3390/v10100567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213739/
https://www.ncbi.nlm.nih.gov/pubmed/30332797
http://dx.doi.org/10.3390/v10100567

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