Amphiphilic Polymeric Micelles Based on Deoxycholic Acid and Folic Acid Modified Chitosan for the Delivery of Paclitaxel

The present investigation aimed to develop a tumor-targeting drug delivery system for paclitaxel (PTX). The hydrophobic deoxycholic acid (DA) and active targeting ligand folic acid (FA) were used to modify water-soluble chitosan (CS). As an amphiphilic polymer, the conjugate FA-CS-DA was synthesized...

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Detalles Bibliográficos
Autores principales: Li, Liang, Liang, Na, Wang, Danfeng, Yan, Pengfei, Kawashima, Yoshiaki, Cui, Fude, Sun, Shaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213782/
https://www.ncbi.nlm.nih.gov/pubmed/30322014
http://dx.doi.org/10.3390/ijms19103132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213782/
https://www.ncbi.nlm.nih.gov/pubmed/30322014
http://dx.doi.org/10.3390/ijms19103132

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