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Visualization of Tau–Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique

Tau is a neuron-specific microtubule-binding protein that stabilizes microtubules. It is generally thought that highly phosphorylated tau dissociates from microtubules and becomes insoluble aggregates, leading to neuronal degeneration. Due to the implication of tau aggregation in neurodegenerative d...

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Detalles Bibliográficos
Autores principales: Shin, Seulgi, Lim, Sungsu, Jeong, Hyeanjeong, Kwan, Li Ting, Kim, Yun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213793/
https://www.ncbi.nlm.nih.gov/pubmed/30274285
http://dx.doi.org/10.3390/ijms19102978