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Visualization of Tau–Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique
Tau is a neuron-specific microtubule-binding protein that stabilizes microtubules. It is generally thought that highly phosphorylated tau dissociates from microtubules and becomes insoluble aggregates, leading to neuronal degeneration. Due to the implication of tau aggregation in neurodegenerative d...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213793/ https://www.ncbi.nlm.nih.gov/pubmed/30274285 http://dx.doi.org/10.3390/ijms19102978 |