Cargando…

Visualization of Tau–Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique

Tau is a neuron-specific microtubule-binding protein that stabilizes microtubules. It is generally thought that highly phosphorylated tau dissociates from microtubules and becomes insoluble aggregates, leading to neuronal degeneration. Due to the implication of tau aggregation in neurodegenerative d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Seulgi, Lim, Sungsu, Jeong, Hyeanjeong, Kwan, Li Ting, Kim, Yun Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213793/ https://www.ncbi.nlm.nih.gov/pubmed/30274285 http://dx.doi.org/10.3390/ijms19102978

Ejemplares similares

Pan-HDAC Inhibitors Promote Tau Aggregation by Increasing the Level of Acetylated Tau
por: Jeong, Hyeanjeong, et al.
Publicado: (2019)

Levosimendan inhibits disulfide tau oligomerization and ameliorates tau pathology in Tau(P301L)-BiFC mice
por: Lim, Sungsu, et al.
Publicado: (2023)

Bimolecular Fluorescence Complementation; Lighting-Up Tau-Tau Interaction in Living Cells
por: Tak, HyeJin, et al.
Publicado: (2013)

Glioblastoma-secreted soluble CD44 activates tau pathology in the brain
por: Lim, Sungsu, et al.
Publicado: (2018)

Screening of male breast cancer and of breast-ovarian cancer families for BRCA2 mutations using large bifluorescent amplicons
por: Pages, S, et al.
Publicado: (2001)

Tau-tubulin kinase
por: Ikezu, Seiko, et al.
Publicado: (2014)

A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo
por: Chiem, Kevin, et al.
Publicado: (2021)

Metal Ion Effects on Aβ and Tau Aggregation
por: Kim, Anne Claire, et al.
Publicado: (2018)

Cell-based Models To Investigate Tau Aggregation
por: Lim, Sungsu, et al.
Publicado: (2014)

The Fate of Tau Aggregates Between Clearance and Transmission
por: Seitkazina, Assel, et al.
Publicado: (2022)

Effect of tau on the vinblastine-induced aggregation of tubulin
Publicado: (1981)

Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors
por: Lim, Sungsu, et al.
Publicado: (2015)

LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
por: Kawakami, Fumitaka, et al.
Publicado: (2012)

Disease‐Associated Tau Phosphorylation Hinders Tubulin Assembly within Tau Condensates
por: Savastano, Adriana, et al.
Publicado: (2020)

Microtubule-Associated Protein Tau, α-Tubulin and βIII-Tubulin Expression in Breast Cancer
por: Im, Soyoung, et al.
Publicado: (2013)

Tau tubulin kinase 2 is required to initiate mammalian ciliogenesis
por: Goetz, S, et al.
Publicado: (2012)

Tubulin and Tau: Possible targets for diagnosis of Parkinson’s and Alzheimer’s diseases
por: Salama, Mohamed, et al.
Publicado: (2018)

Modified heptapeptide from tau binds both tubulin and microtubules
por: Li, Jingrui, et al.
Publicado: (2020)

Identification of disulfide cross-linked tau dimer responsible for tau propagation
por: Kim, Dohee, et al.
Publicado: (2015)

Plasma tau complements CSF tau and P-tau in the diagnosis of Alzheimer's disease
por: Fossati, Silvia, et al.
Publicado: (2019)

Visualization of protein interactions in living Drosophila embryos by the bimolecular fluorescence complementation assay
por: Hudry, Bruno, et al.
Publicado: (2011)

Two Tau binding sites on tubulin revealed by thiol-disulfide exchanges
por: Martinho, Marlène, et al.
Publicado: (2018)

Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin kinase 2
por: Bernatik, Ondrej, et al.
Publicado: (2020)

Development of an Aryloxazole Derivative as a Brain-Permeable Anti-Glioblastoma Agent
por: Shin, Seulgi, et al.
Publicado: (2019)

Near-Infrared Photobiomodulation of Living Cells, Tubulin, and Microtubules In Vitro
por: Staelens, Michael, et al.
Publicado: (2022)

Tau tubulin kinase is required for spermatogenesis and development of motile cilia in planarian flatworms
por: Magley, Robert Alan, et al.
Publicado: (2019)

Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis
por: Bashore, Frances M., et al.
Publicado: (2023)

Identification of Novel Tau-Tubulin Kinase 2 Inhibitors Using Computational Approaches
por: Ahamad, Shahzaib, et al.
Publicado: (2023)

Methylene Blue Delivery Mediated by Focused Ultrasound-Induced Blood–Brain Barrier Disruption Reduces Neural Damage and Amyloid-Beta Plaques by AQP-4 Upregulation
por: Choi, Hyo Jin, et al.
Publicado: (2022)

The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43
por: Liachko, Nicole F., et al.
Publicado: (2014)

Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
por: Hernández-Vega, Amayra, et al.
Publicado: (2017)

Imbalanced Expression of Tau and Tubulin Induces Neuronal Dysfunction in C. elegans Models of Tauopathy
por: Miyasaka, Tomohiro, et al.
Publicado: (2018)

Role of Phosphorylation and Hyperphosphorylation of Tau in Its Interaction with βα Dimeric Tubulin Studied from a Bioinformatics Perspective
por: Dixit, Hrushikesh, et al.
Publicado: (2021)

γ-Tubulin–γ-Tubulin Interactions as the Basis for the Formation of a Meshwork
por: Rosselló, Catalina Ana, et al.
Publicado: (2018)

Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice
por: Yukawa, Kayo, et al.
Publicado: (2023)

Blinking Fluorescent Probes for Tubulin Nanoscopy in Living and Fixed Cells
por: Gerasimaitė, Ru̅ta, et al.
Publicado: (2021)

Tubulin isotype regulation maintains asymmetric requirement for α-tubulin over β-tubulin
por: Wethekam, Linnea C., et al.
Publicado: (2023)

Differential binding affinity of tau repeat region R2 with neuronal-specific β-tubulin isotypes
por: Bhandare, Vishwambhar Vishnu, et al.
Publicado: (2019)

Single Posttranslational Modifications in the Central Repeat Domains of Tau4 Impact its Aggregation and Tubulin Binding
por: Ellmer, Doris, et al.
Publicado: (2019)

Modeling the Colchicum autumnale Tubulin and a Comparison of Its Interaction with Colchicine to Human Tubulin
por: Spasevska, Ivana, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_m7u52srquifvv2gv5da2vb18kc