QSAR and Classification Study on Prediction of Acute Oral Toxicity of N-Nitroso Compounds

To better understand the mechanism of in vivo toxicity of N-nitroso compounds (NNCs), the toxicity data of 80 NNCs related to their rat acute oral toxicity data (50% lethal dose concentration, LD(50)) were used to establish quantitative structure-activity relationship (QSAR) and classification model...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Tengjiao, Sun, Guohui, Zhao, Lijiao, Cui, Xin, Zhong, Rugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213880/
https://www.ncbi.nlm.nih.gov/pubmed/30282923
http://dx.doi.org/10.3390/ijms19103015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213880/
https://www.ncbi.nlm.nih.gov/pubmed/30282923
http://dx.doi.org/10.3390/ijms19103015

Ejemplares similares