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Mouse Gamma Herpesvirus MHV-68 Induces Severe Gastrointestinal (GI) Dilatation in Interferon Gamma Receptor-Deficient Mice (IFNγR(−/−)) That Is Blocked by Interleukin-10

Inflammatory bowel disease (IBD) and Clostridium difficile infection cause gastrointestinal (GI) distension and, in severe cases, toxic megacolon with risk of perforation and death. Herpesviruses have been linked to severe GI dilatation. MHV-68 is a model for human gamma herpesvirus infection induci...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Bartee, Mee Yong, Yaron, Jordan R., Liu, Liying, Zhang, Liqiang, Zheng, Donghang, Hogue, Ian B., Bullard, Whitney L., Tibbetts, Scott, Lucas, Alexandra R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213885/
https://www.ncbi.nlm.nih.gov/pubmed/30249047
http://dx.doi.org/10.3390/v10100518