A High-Content Screening Assay for the Discovery of Novel Proteasome Inhibitors from Formosan Soft Corals

The ubiquitin-proteasome system (UPS) is a major proteolytic pathway that safeguards protein homeostasis. The main 26S proteasome consists of a 20S catalytic core proteasome and a 19S substrate recognition proteasome. UPS dysfunction underlies many important clinical diseases involving inflammation,...

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Detalles Bibliográficos
Autores principales: Ling, Xue-Hua, Wang, Shang-Kwei, Huang, Yun-Hsuan, Huang, Min-Jay, Duh, Chang-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213913/
https://www.ncbi.nlm.nih.gov/pubmed/30347865
http://dx.doi.org/10.3390/md16100395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213913/
https://www.ncbi.nlm.nih.gov/pubmed/30347865
http://dx.doi.org/10.3390/md16100395

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