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Polyamine Metabolism and Gene Methylation in Conjunction with One-Carbon Metabolism
Recent investigations have revealed that changes in DNA methylation status play an important role in aging-associated pathologies and lifespan. The methylation of DNA is regulated by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b) in the presence of S-adenosylmethionine (SAM), which serves as a m...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213949/ https://www.ncbi.nlm.nih.gov/pubmed/30309036 http://dx.doi.org/10.3390/ijms19103106 |