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Identification of Enolase as the Target of 2-Aminothiazoles in Mycobacterium tuberculosis

Tuberculosis is a massive global burden and Mycobacterium tuberculosis is increasingly resistant to first- and second-line drugs. There is an acute need for new anti-mycobacterial drugs with novel targets. We previously evaluated a series of 2-aminothiazoles with activity against Mycobacterium tuber...

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Detalles Bibliográficos
Autores principales: Wescott, Heather H., Zuniga, Edison S., Bajpai, Anumita, Trujillo, Carolina, Ehrt, Sabine, Schnappinger, Dirk, Roberts, David M., Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213970/
https://www.ncbi.nlm.nih.gov/pubmed/30416491
http://dx.doi.org/10.3389/fmicb.2018.02542