Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum

N-Acetyl-d-neuraminic acid lyase (NanA) catalyzes the breakdown of sialic acid (Neu5Ac) to N-acetyl-d-mannosamine (ManNAc) and pyruvate. NanA plays a key role in Neu5Ac catabolism in many pathogenic and bacterial commensals where sialic acid is available as a carbon and nitrogen source. Several path...

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Detalles Bibliográficos
Autores principales: Kumar, Jay Prakash, Rao, Harshvardhan, Nayak, Vinod, Ramaswamy, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213981/
https://www.ncbi.nlm.nih.gov/pubmed/30387778
http://dx.doi.org/10.1107/S2053230X18012992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213981/
https://www.ncbi.nlm.nih.gov/pubmed/30387778
http://dx.doi.org/10.1107/S2053230X18012992

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