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Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum
N-Acetyl-d-neuraminic acid lyase (NanA) catalyzes the breakdown of sialic acid (Neu5Ac) to N-acetyl-d-mannosamine (ManNAc) and pyruvate. NanA plays a key role in Neu5Ac catabolism in many pathogenic and bacterial commensals where sialic acid is available as a carbon and nitrogen source. Several path...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213981/ https://www.ncbi.nlm.nih.gov/pubmed/30387778 http://dx.doi.org/10.1107/S2053230X18012992 |