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Novel Potentials of the DPP-4 Inhibitor Sitagliptin against Ischemia-Reperfusion (I/R) Injury in Rat Ex-Vivo Heart Model

Dipeptidyl peptidase-4 (DPP-4) inhibitors are a class of oral anti-diabetic drugs, implicated in pleiotropic secondary cardioprotective effects. The aim of the study was to unveil the unknown and possible cardioprotective targets that can be exerted by sitagliptin (Sitg) against ischemia-reperfusion...

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Detalles Bibliográficos
Autores principales: Al-awar, Amin, Almási, Nikoletta, Szabó, Renáta, Takacs, Istvan, Murlasits, Zsolt, Szűcs, Gergő, Török, Szilvia, Pósa, Anikó, Varga, Csaba, Kupai, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213995/
https://www.ncbi.nlm.nih.gov/pubmed/30340421
http://dx.doi.org/10.3390/ijms19103226