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Dendrimeric Poly(Epsilon-Lysine) Delivery Systems for the Enhanced Permeability of Flurbiprofen across the Blood-Brain Barrier in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive brain disorder and age-related disease characterised by abnormal accumulation of β-amyloid (Aβ). The development of drugs to combat AD is hampered by the lack of therapeutically-active molecules able to cross the blood-brain barrier (BBB). It is agreed that...

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Detalles Bibliográficos
Autores principales: Al-azzawi, Shafq, Masheta, Dhafir, Guildford, Anna L., Phillips, Gary, Santin, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214014/
https://www.ncbi.nlm.nih.gov/pubmed/30340406
http://dx.doi.org/10.3390/ijms19103224