Cargando…
Dendrimeric Poly(Epsilon-Lysine) Delivery Systems for the Enhanced Permeability of Flurbiprofen across the Blood-Brain Barrier in Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive brain disorder and age-related disease characterised by abnormal accumulation of β-amyloid (Aβ). The development of drugs to combat AD is hampered by the lack of therapeutically-active molecules able to cross the blood-brain barrier (BBB). It is agreed that...
Autores principales: | Al-azzawi, Shafq, Masheta, Dhafir, Guildford, Anna L., Phillips, Gary, Santin, Matteo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214014/ https://www.ncbi.nlm.nih.gov/pubmed/30340406 http://dx.doi.org/10.3390/ijms19103224 |
Ejemplares similares
-
A Peptide-Based Nanocarrier for an Enhanced Delivery and Targeting of Flurbiprofen into the Brain for the Treatment of Alzheimer’s Disease: An In Vitro Study
por: Al-azzawi, Shafq, et al.
Publicado: (2020) -
Designing and Characterization of a Novel Delivery System for Improved Cellular Uptake by Brain Using Dendronised Apo-E-Derived Peptide
por: Al-azzawi, Shafq, et al.
Publicado: (2019) -
Tuning the Activity of Anoplin by Dendrimerization
of Lysine and Lipidation of the N-Terminal
por: Gou, Sanhu, et al.
Publicado: (2021) -
Hyperbranched poly(ϵ-lysine) substrate presenting the laminin sequence YIGSR induces the formation of spheroids in adult bone marrow stem cells
por: Perugini, Valeria, et al.
Publicado: (2017) -
Amoebicidal Activity of Poly-Epsilon-Lysine Functionalized Hydrogels
por: Kennedy, Stephnie M., et al.
Publicado: (2022)