The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells

Chemoresistance is a major limiting factor that impairs the outcome of non-small cell lung cancer (NSCLC) chemotherapy. Paclitaxel (Tax) induces protective autophagy in NSCLC cells, leading to the development of drug resistance. We recently identified a new autophagy inhibitor (alpha-hederin) and hy...

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Detalles Bibliográficos
Autores principales: Zhan, Yujuan, Wang, Kun, Li, Qiao, Zou, Yidan, Chen, Bonan, Gong, Qing, HO, Hiuting Idy, Yin, Ting, Zhang, Fangyuan, Lu, Yuhua, Wu, Weijie, Zhang, Yilin, Tan, Yuhui, Du, Biaoyan, Liu, Xiaodong, Xiao, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214018/
https://www.ncbi.nlm.nih.gov/pubmed/30340379
http://dx.doi.org/10.3390/ijms19103221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214018/
https://www.ncbi.nlm.nih.gov/pubmed/30340379
http://dx.doi.org/10.3390/ijms19103221

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